Talk:Cystic fibrosis

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Cystic fibrosis is a former featured article. Please see the links under Article milestones below for its original nomination page (for older articles, check the nomination archive) and why it was removed.

This article appeared on Wikipedia's Main Page as Today's featured article on July 6, 2006.

Article milestones
Date	Process	Result
June 1, 2006	Peer review	Reviewed
June 10, 2006	Featured article candidate	Promoted
January 5, 2010	Featured article review	Demoted
April 30, 2010	Good article nominee	Not listed
Current status: Former featured article

Medicine: Genetics / Pulmonology High‑importance

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Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Cystic fibrosis.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

Wiki Education Foundation-supported course assignment

This article was the subject of a Wiki Education Foundation-supported course assignment, between 19 August 2019 and 13 December 2019. Further details are available on the course page. Student editor(s): Katjenkins0520. Peer reviewers: Micheladitmore.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 18:55, 16 January 2022 (UTC)[reply]

Problematic picture at top of entry

It is problematic that the image at the top of the page is of clubbed fingers. That is something that only some people with CF have. It would make much more sense to have a picture of lungs at the top, since that is a feature of CF that is the most common. Alternatively, an illustration of the genetic defect would work. Could someone please move the picture of clubbed fingers lower on the page and put something more relevant at the top? CanadianJane (talk) 16:08, 3 August 2018 (UTC)[reply]

Not really problematic. It is a classic finding and present in about 80% of people with the condition. Doc James (talk · contribs · email) 12:56, 4 August 2018 (UTC)[reply]

Ursodeoxycholic acid

I have reincorporated a source that was initially deleted as primary. It is an editorial that accompanied the publication of a study. It was used for context. I moved the entire section to treatment and am using the editorial for the context not included in the Cochrane review. I hope this passes muster. BiologicalMe (talk) 14:48, 5 September 2018 (UTC)[reply]

"Any physical contact [with others with CF] poses a serious cross infection risk"

This article https://www.bbc.co.uk/news/av/disability-42358852/the-choir-that-can-never-sing-together states that "Any physical contact [with others with CF] poses a serious cross infection risk" and should therefore be avoided. Is this generally accepted? Would this be useful info to add to this article, in the Management section section for example? FrankSier (talk) 22:48, 15 September 2018 (UTC)[reply]

New drug Trikafta

Would someone with more knowledge than I please add a section on this new drug. It is getting lots of press including here: https://www.washingtonpost.com/health/2019/10/31/long-awaited-cystic-fibrosis-drug-could-turn-deadly-disease-into-manageable-condition/ — Preceding unsigned comment added by 128.125.185.134 (talk) 19:32, 31 October 2019 (UTC)[reply]

Statement of intent

So, I've been retired for 8 years. In the meantime, I've spent 5 years working as a researcher in this field and this article is dangerously out of date. In that time I've also forgotten all of the policies that I used to be able to type out in my sleep. I'd appreciate any help as I try cleaning up and overhauling this article to reflect the (much more positive!) current state of CF knowledge and treatment. Danger ^{High voltage!} 16:18, 25 September 2021 (UTC)[reply]

Hi @Danger: i was just reading this talk page. Did you have any success? Are there some areas/sections that you want to list here and maybe we can try to gather some secondary sources and tackle anything else. JenOttawa (talk) 21:10, 8 May 2023 (UTC)[reply]

'Comorbidities' and Intracellular electrolytes section contains no references and seems quite anecdotal/opinionated

I am not suitably qualified to feel comfortable removing this but it is not clearly based on fact.

'Comorbidities' and Intracellular electrolytes.

Persons with CF show an extraordinary number of "comorbidities" affecting almost every organ in the body. These have in the past been viewed as incidental and not caused directly by the faulty CFTR gene but that should be reconsidered. If Chloride is not being pumped out of cells because of the faulty CFTR channel, then the levels within the cells will be high and will need be balanced by increased cations (Potassium and Calcium in particular). High Calcium in the parathyroid cells may be expected to affect the function of that gland and so too the bones, causing hypoporosis. High intracellular potassium may be expected to affect Adrenal function causing hypokalaemia. Muscle activity may be affected by these electrolyte abnormalities including cardiomyopathy of the heart. Nerve function is affected by electrolytes esp. Potassium. The endocrine cells of the Pancreas that produce Insulin, in the Islets of Lanaghans, may be affected too. Our personal experience is that the response to treatment of Hypoglycemia is better if glucose is given in an electrolyte drink.

More research is needed into intracellular electrolytes in pwCF. We may well find the CFTR gene affects EVERY cell in the body not just those producing mucous. 118.93.131.49 (talk) 15:41, 31 May 2023 (UTC)[reply]

From https://x.com/sarahzhang/status/1765798523512012861 and https://www.drugs.com/trikafta.html it seems like this article statement that there is no cure isn't really true anymore? Should this be updated?

Boxed (talk) 13:38, 21 May 2024 (UTC)[reply]